Monica Javidnia


University of Rochester

I'm a pharmacologist in Rochester, NY studying Parkinson’s disease and dementia disease modeling and simulation.

Monica has shared 2 notes

LATE is a newly defined brain disorder that mimics the symptoms of Alzheimer's disease

Walking the walk but not talking the talk, limbic-predominant age-related TDP-43 encephalopathy (LATE) is a newly defined brain disorder that mimics Alzheimer's disease (AD). Both LATE and AD share common symptoms, but the underlying protein pathology differs between the two diseases. In AD, the two major proteins associated with disease are amyloid beta and tau, forming plaques and tangles, respectively. However, in LATE, the major protein is TDP-43, a protein linked to diseases like ALS and frontotemporal dementia.

One-quarter of people 85 and older are estimated to have LATE, meaning that they have enough TDP-43 in certain parts of the brain to impair cognition. The identification of LATE could have major implications for disease diagnosis and clinical research. 

How can we improve the postdoc experience? Notes from the NPA Annual Meeting!

Numerous institutions have their postdoctoral fellows and administrators returning this week from the National Postdoctoral Association Annual Meeting (April 12-14) in Orlando, Florida. 

A group of people posing for a photo seated at a circular table. One is holding a paper sign that reads "Postdoc Leaders."

Postdoc leaders at the meeting, including the author (3rd from the left, holding the sign)

The meeting was a perfect balance of career development sessions, interactive workshops, and opportunities for meaningful networking, with presentations including "Did They Really Just Say That?! Responding to Bias at Work", "NSF Postdoctoral Research Fellowships: Strategies for Success", and mealtime meetups for general or specific groups. The poster viewing session had us furiously scribbling down ideas to bring back to our respective campuses such as PENNView, a postdoctoral diversity initiative to expose Mid-Atlantic doctoral candidates to research at the University of Pennsylvania. Another poster by Ralph J. Hazlewood shared their successful methods for increasing postdoc engagement and attendance at Vanderbilt University. I know I speak for many attendees when I say I'm excited to share what I have learned and improve the postdoc experience! Hope to see y'all at the 2020 meeting in San Diego.